Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 10/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23891729 | 0.89 | EP300 (0.33) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891672 | 0.85 | CCKBR (0.34) | NPC1RAB9AEP300CREBBPCYP3A4 | |
| SCHEMBL23891707 | 0.83 | EP300 (0.49) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891583 | 0.71 | EP300 (0.46) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL24350741 | 0.70 | EP300 (0.46) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891727 | 0.70 | EP300 (0.45) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23891706 | 0.70 | — | — | |
| SCHEMBL23891650 | 0.70 | CYP3A4 (0.35) | CYP3A4POLB | |
| SCHEMBL23891578 | 0.70 | CYP3A4 (0.35) | CYP3A4POLB | |
| SCHEMBL23891728 | 0.68 | CYP3A4 (0.34) | CREBBPCYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |