Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.49 |
| ▸ | CTSG | P08311 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755116 | 0.82 | ELANE (0.50) | ELANEPRTN3CTSGLMNAAR | |
| Ethadione SCHEMBL35279 | 0.75 | ELANE (0.55) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL4757301 | 0.74 | ELANE (0.53) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL7309157 | 0.74 | ELANE (0.53) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL14009928 | 0.72 | LMNA (0.54) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL5006337 | 0.71 | ELANE (0.54) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL13622590 | 0.71 | ELANE (0.50) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL13188868 | 0.71 | LMNA (0.52) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL4755111 | 0.71 | ELANE (0.50) | ELANEPRTN3CTSGLMNAAR | |
| SCHEMBL6642820 | 0.69 | ELANE (0.49) | ELANEPRTN3CTSGLMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |