Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 12/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | PRNP | P04156 | 5/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548432 | 0.85 | ACMSD (0.68) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL22176152 | 0.85 | ACMSD (0.70) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053408 | 0.80 | ACMSD (0.69) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23852766 | 0.80 | ACMSD (0.69) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL17548497 | 0.80 | ACMSD (1.00) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053424 | 0.80 | ACMSD (0.76) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23849818 | 0.80 | ACMSD (0.76) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23850316 | 0.80 | ACMSD (0.78) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053420 | 0.80 | ACMSD (0.78) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23850223 | 0.79 | ACMSD (0.78) | ACMSDCYP2C19MEN1KMT2APRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186242-B1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S R L (IT) | 2021-10-06 | — | — | EP | disclosed |