Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.90 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL16857350 | 1.00 | ALDH1A1 (0.90) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4821241 | 0.97 | ALDH1A1 (0.95) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4821237 | 0.97 | KDM4E (0.85) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4819900 | 0.97 | ALDH1A1 (0.95) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL309119 | 0.97 | ALDH1A1 (0.95) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Iodide SCHEMBL16857345 | 0.97 | ALDH1A1 (0.85) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL1250694 | 0.97 | KDM4E (0.85) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL1484108 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| Hydrogen Sulfide SCHEMBL5998720 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL28168 | 0.97 | ALDH1A1 (0.94) | ALDH1A1KDM4ETDP1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1094 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260140444-A1 | PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2026-05-21 | — | — | US | claimed |
| CN-116177558-B | Zirconium-silicon CHA molecular sieve and preparation method and application thereof | 国家能源集团科学技术研究院有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119638749-A | Method for synthesizing NLD-02 flame retardant from neopentyl glycol and phosphorus trichloride in solvent-free system | 乐平市远大化工有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119264130-A | Preparation method of apixaban and intermediate thereof | 浙江华海药业股份有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-119118869-A | Recovery method of 2-cyano-2-valproic acid | 湖南省湘中制药有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-119081025-A | Strong-tensile hydrogel based on aromatic eutectic ionic liquid amphoteric lignin nano particles and preparation method thereof | 辽宁大学 | 2024-12-06 | — | — | CN | claimed |
| CN-119072208-A | Bendable perovskite solar cell based on high-reflection-resistance electrode and preparation method thereof | 大连交通大学 | 2024-12-03 | — | — | CN | claimed |
| CN-116395713-B | Preparation method of Li-SSZ-13 zeolite molecular sieve | 南京工业大学 | 2024-09-03 | — | — | CN | claimed |
| CN-117924347-A | Preparation method of monosulfur organosilane coupling agent | 江西宏柏新材料股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117701107-A | Intrinsic anti-corrosion antibacterial graphene coating and preparation method and application thereof | 宁波市电力设计院有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-1269375-A | Preparation of cyclohexannoe-lower aldehyde epoxy resin | YUEYANG PETROCHEMICAL PLANT BA (CN) | 2000-10-11 | — | — | CN | claimed |
| CN-1036388-C | Process for synthesis of aldehyde by hydroformylation of olefins | LANZHOU OIL REFINERY CHEMICAL (CN) | 1997-11-12 | — | — | CN | claimed |
| EP-0553111-B1 | THIN FILM COMPOSITE ULTRAFILTRATION MEMBRANE | ALLIED SIGNAL INC (US) | 1995-09-06 | — | — | EP | claimed |
| CN-1088905-A | The method of synthesis of aldehyde by hydroformylation of olefins | LANZHOU PETROLEUM PROCESSING C (CN) | 1994-07-06 | — | — | CN | claimed |
| US-5145584-A | Polymer anions and cations for membrane | ALLIED-SIGNAL INC. (US) | 1992-09-08 | — | — | US | claimed |
| US-5145889-A | For light-emitting diodes | KABUSHIKI KAISHA TOSHIBA (JP) | 1992-09-08 | — | — | US | claimed |
| US-5085775-A | Casting solution of polyelectrolyte complex on microporous support; asymmetric; separation of low molecular weight solutes | ALLIED-SIGNAL INC. (US) | 1992-02-04 | — | — | US | claimed |
| US-4102912-A | Process to prepare polyhalodiphenyl carbonates | GENERAL ELECTRIC COMPANY (US) | 1978-07-25 | — | — | US | claimed |
| US-3959345-A | FROM CYANOACETYLENE AND HYDROGEN CYANIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-05-25 | — | — | US | claimed |
| US-3957517-A | Dry stabilization of a silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260140444-A1 | PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | INO80C, INO80, NAT10 | CHRM1 188/4885ALDH1A1 2819/4885KDM4E 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.