Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25901353 | 0.94 | PCSK9 (0.36) | PCSK9PPARGPPARATHRBTHRA | |
| SCHEMBL25901069 | 0.90 | PCSK9 (0.35) | PCSK9PPARGPPARATHRBTHRA | |
| SCHEMBL23395575 | 0.86 | PCSK9 (0.32) | PCSK9THRB | |
| SCHEMBL26291717 | 0.85 | PCSK9 (0.34) | PCSK9PPARGPPARATHRBTHRA | |
| SCHEMBL21735266 | 0.83 | PCSK9 (0.33) | PCSK9PPARGPPARATHRB | |
| SCHEMBL26291712 | 0.83 | PCSK9 (0.36) | PCSK9PPARGPPARATHRBTHRA | |
| SCHEMBL25901064 | 0.83 | PCSK9 (0.36) | PCSK9PPARGPPARATHRBCSNK1D | |
| SCHEMBL23893466 | 0.82 | PCSK9 (0.32) | PCSK9 | |
| SCHEMBL26292514 | 0.82 | TSHR (0.41) | PCSK9PPARGPPARATHRBTHRA | |
| SCHEMBL21735301 | 0.82 | PCSK9 (0.32) | PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |