Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395687 | 0.90 | PCSK9 (0.36) | PCSK9PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL23395721 | 0.88 | PCSK9 (0.34) | PCSK9PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL21735847 | 0.88 | HTR2A (0.39) | PCSK9PPARGPPARACSNK1D | |
| SCHEMBL26292240 | 0.87 | PCSK9 (0.35) | PCSK9PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL25901353 | 0.86 | PCSK9 (0.36) | PCSK9PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL21735525 | 0.84 | ESR1 (0.45) | PCSK9PPARGPPARAESR1ESR2 | |
| SCHEMBL23893545 | 0.83 | PCSK9 (0.35) | PCSK9PPARGPPARACSNK1DTHRB | |
| SCHEMBL25896937 | 0.82 | PCSK9 (0.35) | PCSK9PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL25901069 | 0.82 | PCSK9 (0.35) | PCSK9PPARGPPARACSNK1DTHRB | |
| SCHEMBL21735605 | 0.81 | MEN1 (0.37) | PCSK9PPARGS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |