Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26298661 | 0.83 | MTNR1A (0.43) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL23395720 | 0.82 | MTNR1A (0.41) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL21735533 | 0.82 | GRIK1 (0.58) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL26292361 | 0.81 | MTNR1A (0.46) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL23893479 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL23893476 | 0.77 | MTNR1A (0.41) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL21735542 | 0.76 | BACE1 (0.51) | MTNR1AMTNR1BBACE1L3MBTL1ALDH1A1 | |
| SCHEMBL22630103 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL21735706 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 | |
| SCHEMBL23395710 | 0.75 | MTNR1A (0.40) | MTNR1AMTNR1BBACE1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |