Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034413 | 0.84 | DPP4 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL24178937 | 0.84 | DPP4 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL23893058 | 0.80 | — | — | |
| SCHEMBL25584365 | 0.75 | DPP4 (0.31) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL22387696 | 0.74 | — | — | |
| SCHEMBL6671727 | 0.72 | — | — | |
| SCHEMBL271971 | 0.72 | — | — | |
| SCHEMBL2568464 | 0.72 | — | — | |
| SCHEMBL2512216 | 0.72 | — | — | |
| SCHEMBL9651237 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889145-A1 | 8-CYANO-5-PIPERIDINO-QUINOLINES AS TLR7/8 ANTAGONISTS AND THEIR USES FOR TREATING IMMUNE DISORDERS | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |