⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671727 | 1.00 | — | — | |
| SCHEMBL892804 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4771535 | 0.97 | DPP4 (0.50) | — | |
| Hydrochloric Acid SCHEMBL19900820 | 0.97 | DPP4 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL27230994 | 0.85 | SLC7A5 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL27210261 | 0.85 | SLC7A5 (0.43) | — | |
| SCHEMBL19503059 | 0.84 | DPP4 (0.53) | — | |
| SCHEMBL19522543 | 0.84 | DPP4 (0.53) | — | |
| SCHEMBL20990277 | 0.82 | DPP4 (0.52) | — | |
| Trifluoroacetic Acid SCHEMBL27923223 | 0.82 | DPP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2013-08-15 | — | — | US | claimed |
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2010-09-16 | — | — | US | claimed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |
| US-20080139561-A1 | e.g. 6-(5-Cyclopropyl-1H-pyrazol-3-ylamino)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino) nicotinonitrile; tropomyosin-related kinases (Trk's) inhibitor; anticarcinogenic agent; hormone related cancer, leukemia; antiinflammatory agent; arthritis, restenosis; autoimmune diseases | ASTRAZENECA AB (SE) | 2008-06-12 | — | — | US | claimed |
| EP-1846394-A1 | PYRAZOLYLAMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS | AstraZeneca AB (SE) | 2007-10-24 | — | — | EP | claimed |
| WO-2006082392-A1 | PYRAZOLYLAMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-08-10 | — | — | WO | claimed |
| US-6486193-B2 | ANTIARTHRITIC AGENTS; ANTIINFLAMMATORY AGENTS | AVENTIS PHARMACEUTICALS INC. | 2002-11-26 | — | — | US | claimed |
| US-20020037859-A1 | 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases | AVENTISUB INC. | 2002-03-28 | — | — | US | claimed |
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| CN-115920078-A | Antibody drug conjugates targeting claudin 18.2 | 礼新医药科技(上海)有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20230053342-A1 | IMIDAZOLIDINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2023-02-23 | — | — | US | disclosed |
| CN-112047815-B | Preparation method of cannabidiol compound | 成都海博为药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-11530226-B2 | Azepane inhibitors of menin-MLL interaction | JANSSEN PHARMACEUTICA NV (BE) | 2022-12-20 | — | — | US | disclosed |
| CN-1258301-A | Antiviral protease inhibitors | MEDIVIR AB (SE) | 2000-06-28 | — | — | CN | disclosed |
| EP-1005493-A1 | ANTIVIRAL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2000-06-07 | — | — | EP | disclosed |
| EP-0977730-A1 | AMINO ACID DERIVATIVES INHIBITING EXTRACELLULAR MATRIX METALLOPROTEINASE AND TNF ALPHA RELEASE | CHIESI FARMACEUTICI S.p.A. (IT) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047863-A1 | AMINO ACID DERIVATIVES INHIBITING EXTRACELLULAR MATRIX METALLOPROTEINASE AND TNF ALPHA RELEASE | CHIESI FARMACEUTICI S.P.A. (IT) | 1998-10-29 | — | — | WO | disclosed |
| WO-1998045330-A1 | ANTIVIRAL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 1998-10-15 | — | — | WO | disclosed |