Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908447 | 1.00 | MAOB (0.58) | MAOBEPHX2GPR35CYP1A2HDAC3 | |
| SCHEMBL11428736 | 0.90 | EPHX2 (0.68) | EPHX2GPR35TGM2NPC1RAB9A | |
| SCHEMBL3462701 | 0.87 | MAOB (0.61) | MAOBEPHX2CYP1A2HDAC3ADAM17 | |
| SCHEMBL3462699 | 0.87 | MAOB (0.61) | MAOBEPHX2CYP1A2HDAC3ADAM17 | |
| SCHEMBL23880578 | 0.81 | PTPN1 (0.63) | MAOBGPR35HDAC1PTPN1PTPN11 | |
| SCHEMBL23880577 | 0.81 | PTPN1 (0.63) | MAOBGPR35HDAC1PTPN1PTPN11 | |
| SCHEMBL23880554 | 0.81 | PTPN1 (0.74) | PTPN1PTPN6PTPN11 | |
| SCHEMBL23880562 | 0.81 | EPHX2 (0.56) | EPHX2GPR35NPC1RAB9ADHODH | |
| SCHEMBL2518624 | 0.80 | EPHX2 (0.76) | EPHX2TGM2NPC1RAB9ADHODH | |
| SCHEMBL9634100 | 0.78 | MAOB (0.75) | MAOBEPHX2CYP1A2HDAC3ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297860-B | Novel N-aryl oxamic acids | 普渡研究基金会 | 2024-10-15 | — | — | CN | disclosed |
| CN-115297860-A | Novel N-aryl-oxalamic acids | 普渡研究基金会 | 2022-11-04 | — | — | CN | disclosed |
| US-11192850-B2 | N-aryl oxamic acids | PURDUE RESEARCH FOUNDATION (US) | 2021-12-07 | — | — | US | disclosed |
| US-20210309606-A1 | Novel N-aryl Oxamic Acids | PURDUE RESEARCH FOUNDATION (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309606-A1 | Novel N-aryl Oxamic Acids | PTPRB, PTPRO, PTPRM | MAOB 43/4885EPHX2 2020/4885GPR35 2744/4885 |
| US-11192850-B2 | N-aryl oxamic acids | PTPRB, PTPRO, PTPRM | MAOB 33/4885EPHX2 2092/4885GPR35 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.