Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18375567 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4963249 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4960479 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4960482 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4963254 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL10863313 | 0.86 | MAPT (0.61) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4959548 | 0.86 | NPSR1 (0.65) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4959550 | 0.86 | NPSR1 (0.65) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4960671 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL4960676 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202688-A1 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | GILEAD SCIENCES, INC. (US) | 2021-10-07 | — | — | WO | disclosed |