⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26148323 | 0.84 | TSHR (0.42) | — | |
| SCHEMBL27783595 | 0.80 | TSHR (0.39) | — | |
| Ethane SCHEMBL10937833 | 0.77 | THRB (0.32) | — | |
| Hydrochloric Acid SCHEMBL5595146 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL14104484 | 0.74 | THRB (0.31) | — | |
| SCHEMBL14681108 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL6058466 | 0.73 | — | — | |
| SCHEMBL7676723 | 0.72 | — | — | |
| SCHEMBL312390 | 0.72 | — | — | |
| SCHEMBL1190532 | 0.72 | KDM4C (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119782-A1 | METHOD FOR THE MANUFACTURE OF NEW AMINE | EVONIK OPERATIONS GMBH (DE) | 2025-06-12 | — | — | WO | claimed |
| US-4042642-A | 1,3-BIS(MORPHOLINOTHIO)-IMIDAZOLIDINONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-3960857-A | Urea additives for sulfur vulcanizable polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-01 | — | — | US | claimed |
| US-20260108521-A1 | GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2026-04-23 | — | — | US | disclosed |
| EP-4598918-A1 | GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2025-08-13 | — | — | EP | disclosed |
| WO-2025119782-A1 | METHOD FOR THE MANUFACTURE OF NEW AMINE | EVONIK OPERATIONS GMBH (DE) | 2025-06-12 | — | — | WO | disclosed |
| WO-2024073871-A1 | GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024073871-A1 | GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2024-04-11 | — | — | WO | disclosed |
| US-9422308-B2 | Derivatives of docosahexaenoylethanolamide and uses thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150031878-A1 | DERIVATIVES OF DOCOSAHEXAENOYLETHANOLAMIDE AND USES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2015-01-29 | — | — | US | disclosed |
| US-8318736-B2 | HIV inhibiting 5,6-substituted pyrimidines | JANSSEN R&D IRELAND (IE) | 2012-11-27 | — | — | US | disclosed |
| EP-1324985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028831-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-0392160-A1 | Azole-1-alkanamides as antiarrhythmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-10-17 | — | — | EP | disclosed |
| US-4962120-A | ANTIARRHYTHMIA AGENTS | STERLING DRUG INC. (US) | 1990-10-09 | — | — | US | disclosed |
| US-4347075-A | Method for using nicotinic acid derivatives as plant growth regulants | MONSANTO COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4261730-A | ALTER MALE REPRODUCTIVE COMPONENTS OF CORN PLANT | MONSANTO COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4042642-A | 1,3-BIS(MORPHOLINOTHIO)-IMIDAZOLIDINONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-3960857-A | Urea additives for sulfur vulcanizable polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3944552-A | VULCANIZATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-16 | — | — | US | disclosed |