Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664544 | 0.94 | MEN1 (0.40) | CYP2D6CYP2C19ACE2MEN1KMT2A | |
| SCHEMBL6722031 | 0.87 | CYP2D6 (0.44) | CYP2D6CYP2C19ACE2SMN1; SMN2USP2 | |
| SCHEMBL4761459 | 0.83 | KDM4E (0.54) | MEN1KMT2AEPHX1USP2TSHR | |
| SCHEMBL20836565 | 0.83 | CYP2D6 (0.52) | CYP2D6CYP2C19ACE2MEN1KMT2A | |
| SCHEMBL14492895 | 0.83 | KDM4E (0.54) | MEN1KMT2AEPHX1USP2TSHR | |
| SCHEMBL3874259 | 0.83 | CYP2D6 (0.41) | CYP2D6CYP2C19ACE2MEN1KMT2A | |
| SCHEMBL13056218 | 0.82 | DPP7 (0.38) | ACE2MEN1KMT2AGAAEPHX1 | |
| SCHEMBL5208550 | 0.82 | MEN1 (0.35) | ACE2MEN1KMT2AGAAEPHX1 | |
| SCHEMBL23710264 | 0.82 | DPP7 (0.38) | ACE2MEN1KMT2AGAAEPHX1 | |
| SCHEMBL18829056 | 0.82 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309882-A1 | COATING COMPOSITIONS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-10-07 | — | — | US | disclosed |