Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901022 | 0.94 | CYP2D6 (0.41) | MEN1KMT2ACYP2D6CYP2C19ACE2 | |
| SCHEMBL6722031 | 0.85 | CYP2D6 (0.44) | CYP2D6CYP2C19ACE2SMN1; SMN2USP2 | |
| SCHEMBL9968738 | 0.82 | KDM4E (0.61) | MEN1KMT2AACE2EPHX1KDM4E | |
| SCHEMBL23559874 | 0.82 | KDM4E (0.61) | MEN1KMT2AACE2EPHX1KDM4E | |
| SCHEMBL18723007 | 0.82 | ACHE (0.46) | EPHX1 | |
| SCHEMBL10141101 | 0.81 | CYP2D6 (0.50) | MEN1KMT2ACYP2D6CYP2C19EPHX1 | |
| SCHEMBL23442922 | 0.81 | GNAI3 (0.45) | MEN1KMT2ACYP2D6CYP2C19ACE2 | |
| SCHEMBL18827304 | 0.81 | GNAI3 (0.41) | MEN1KMT2AACE2EPHX1DPP7 | |
| SCHEMBL19468486 | 0.79 | CYP2D6 (0.48) | MEN1KMT2ACYP2D6CYP2C19EPHX1 | |
| SCHEMBL19468487 | 0.79 | CYP2D6 (0.48) | MEN1KMT2ACYP2D6CYP2C19EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227451-A2 | CURABLE ALKOXYCARBONYLAMINO COMPOSITIONS, COATINGS, AND METHODS | BASF Coatings GmbH (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009088834-A2 | CURABLE ALKOXYCARBONYLAMINO COMPOSITIONS, COATINGS, AND METHODS | BASF CORPORATION (US) | 2009-07-16 | — | — | WO | disclosed |