Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.42 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12194054 | 0.86 | ELANE (0.49) | ELANEF2PLAUCTRB1MAP2K4 | |
| SCHEMBL4300088 | 0.86 | ELANE (0.55) | ELANEF2PLAUCTRB1MAP2K4 | |
| SCHEMBL15724312 | 0.85 | ELANE (0.44) | ELANEMAP2K4 | |
| SCHEMBL9952523 | 0.83 | MAP2K4 (0.42) | ELANEF2PLAUMAP2K4 | |
| SCHEMBL13748554 | 0.83 | MAP2K4 (0.44) | ELANEMAP2K4 | |
| SCHEMBL12193518 | 0.82 | ELANE (0.59) | ELANEF2PLAUCTRB1MAP2K4 | |
| SCHEMBL22801674 | 0.81 | MAP2K4 (0.51) | ELANEMAP2K4 | |
| SCHEMBL25994222 | 0.81 | ELANE (0.42) | ELANEMAP2K4 | |
| SCHEMBL15724311 | 0.80 | MAP2K4 (0.40) | ELANEMAP2K4 | |
| SCHEMBL15312268 | 0.80 | GABRG2 (0.41) | ELANEF2PLAUCTRB1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021197467-A1 | MULTI-TARGET ANTI-TUMOR COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华汇拓医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |