Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | CD38 | P28907 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449631 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19681751 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19449632 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19681724 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19437979 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19437984 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19438199 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19437981 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL20938467 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 | |
| SCHEMBL19449630 | 1.00 | HSD11B1 (0.41) | HSD11B1CD38CNR2KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309661-A1 | IMIDAZO[1,5-a]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL - R&D INVESTMENTS, S.A. (PT) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309661-A1 | IMIDAZO[1,5-a]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GAA, GBA2 | HSD11B1 4468/4885CD38 849/4885CNR2 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.