Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | CASP1 | P29466 | 6/20 | 0.39 |
| ▸ | CASP7 | P55210 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19438181 | 0.79 | KDM4E (0.45) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL23901467 | 0.78 | IRAK4 (0.34) | ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL23901519 | 0.75 | KDM4E (0.42) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL19449384 | 0.72 | WDR5 (0.36) | POLB | |
| SCHEMBL19449391 | 0.71 | ANO1 (0.35) | — | |
| SCHEMBL30532267 | 0.70 | ATR (0.43) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL17741205 | 0.70 | ATR (0.43) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL19438382 | 0.69 | ANO1 (0.36) | KDM4EMAPK1MAPTTDP1POLB | |
| SCHEMBL19437972 | 0.69 | KDM4E (0.38) | ALDH1A1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL19438031 | 0.69 | TYRO3 (0.38) | CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309661-A1 | IMIDAZO[1,5-a]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL - R&D INVESTMENTS, S.A. (PT) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309661-A1 | IMIDAZO[1,5-a]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GAA, GBA2 | ALDH1A1 1121/4885MEN1 1938/4885KMT2A 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.