SCHEMBL23901545

SCHEMBL23901545

CC(C)(C)OC(=O)NCCCCOc1ccc(I)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.58
CA1 P00915 7/20 0.58
CA2 P00918 7/20 0.58
CA9 Q16790 7/20 0.58
STK17B O94768 1/20 0.46
STK17A Q9UEE5 1/20 0.46
PDK2 Q15119 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SUCNR1 Q9BXA5 3/20 0.43
IDO1 P14902 2/20 0.43
BRD4 O60885 1/20 0.43
DRD2 P14416 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23901546 0.87 CA12 (0.61) CA12CA1CA2CA9STK17B
SCHEMBL14846343 0.85 CA12 (0.60) CA12CA1CA2CA9STK17B
SCHEMBL25454115 0.84 CA12 (0.56) CA12CA1CA2CA9STK17B
SCHEMBL25454117 0.83 CA12 (0.56) CA12CA1CA2CA9STK17B
SCHEMBL25454118 0.83 CA12 (0.56) CA12CA1CA2CA9STK17B
SCHEMBL29890066 0.81 CA12 (0.56) CA12CA1CA2CA9STK17B
SCHEMBL19000426 0.81 CA12 (0.56) CA12CA1CA2CA9STK17B
SCHEMBL30271526 0.79 ALDH1A1 (0.53) CA12CA1CA2CA9STK17B
SCHEMBL15894974 0.78 CA12 (0.68) CA12CA1CA2CA9PDK2
SCHEMBL14313674 0.78 CA12 (0.70) CA12CA1CA2CA9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021202600-A1 SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ THE SCRIPPS RESEARCH INSTITUTE (US) 2021-10-07 WO disclosed