Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 3/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901527 | 1.00 | AVPR2 (0.40) | AVPR2USP30CYP2C9CYP2C19HTR2B | |
| SCHEMBL25453333 | 0.91 | P2RX7 (0.42) | AVPR2USP30CYP2C9CYP2C19HTR2B | |
| SCHEMBL25453372 | 0.91 | P2RX7 (0.42) | AVPR2USP30CYP2C9CYP2C19HTR2B | |
| SCHEMBL23901480 | 0.90 | AVPR2 (0.42) | AVPR2USP30P2RX7MGLLKRAS | |
| SCHEMBL23901481 | 0.90 | AVPR2 (0.42) | AVPR2USP30P2RX7MGLLKRAS | |
| SCHEMBL25453336 | 0.88 | AVPR2 (0.40) | AVPR2USP30CYP2C9CYP2C19HTR2B | |
| SCHEMBL25453329 | 0.88 | AVPR2 (0.50) | AVPR2USP30P2RX7MGLLNR1H2 | |
| SCHEMBL25453375 | 0.88 | AVPR2 (0.50) | AVPR2USP30P2RX7MGLLNR1H2 | |
| SCHEMBL23901530 | 0.87 | AVPR2 (0.43) | AVPR2USP30P2RX7MGLLKRAS | |
| SCHEMBL25453338 | 0.86 | AVPR2 (0.55) | AVPR2USP30P2RX7MGLLKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | HAVCR2, CD44, ENGASE | AVPR2 4576/4885USP30 545/4885CYP2C9 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.