SCHEMBL23901650

SCHEMBL23901650

COc1cc2c(cc1OC)CN(S)CC2

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.65
MAOA P21397 2/20 0.65
SLC6A4 P31645 1/20 0.65
PDE4D Q08499 1/20 0.57
CA7 P43166 1/20 0.56
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
ABCB1 P08183 1/20 0.51
MAPK1 P28482 1/20 0.51
NPC1 O15118 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
ATM Q13315 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8279050 0.81 MAOB (0.65) MAOBMAOASLC6A4PDE4DCA7
SCHEMBL30634713 0.78 MAOB (1.00) MAOBMAOASLC6A4PDE4DCA7
SCHEMBL14163680 0.78 MAOB (0.67) MAOBMAOASLC6A4PDE4DCA7
SCHEMBL5525085 0.78 MAOB (1.00) MAOBMAOASLC6A4PDE4DCA7
SCHEMBL11169272 0.77 MAOA (0.84) MAOBMAOASLC6A4PDE4DCA7
SCHEMBL12686267 0.77 MAOB (0.65) MAOBMAOASLC6A4PDE4DCA7
Hydrochloric Acid SCHEMBL30634715 0.77 MAOB (0.96) MAOBMAOASLC6A4PDE4DCA7
Hydrochloric Acid SCHEMBL7552906 0.77 MAOB (0.65) MAOBMAOASLC6A4PDE4DCA7
Hydrochloric Acid SCHEMBL20854708 0.77 MAOB (0.96) MAOBMAOASLC6A4PDE4DCA7
SCHEMBL913887 0.76 ABCB1 (0.67) MAOBMAOASLC6A4KMT2AABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021202600-A1 SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ THE SCRIPPS RESEARCH INSTITUTE (US) 2021-10-07 WO disclosed