Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
| ▸ | DRD1 | P21728 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | MC4R | P32245 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11817710 | 0.98 | KCNH2 (0.58) | CYP2D6KCNH2CHRM2ADRA2ACHRM1 | |
| SCHEMBL18901728 | 0.87 | CYP2D6 (0.61) | CYP2D6KCNH2CHRM2ADRA2ACHRM1 | |
| SCHEMBL23901671 | 0.86 | MAOB (0.51) | CYP2D6KCNH2ADRA2ACHRM1MC4R | |
| SCHEMBL4873121 | 0.83 | CYP2C19 (0.73) | CYP2D6KCNH2MAOBGAACYP2C19 | |
| SCHEMBL23496077 | 0.83 | CYP2C19 (0.73) | CYP2D6KCNH2MAOBGAACYP2C19 | |
| SCHEMBL7089852 | 0.83 | CYP2C19 (0.73) | CYP2D6KCNH2MAOBGAACYP2C19 | |
| SCHEMBL18390095 | 0.82 | MC4R (0.62) | CYP2D6KCNH2CHRM2ADRA2ACHRM1 | |
| SCHEMBL9366911 | 0.81 | KCNA5 (0.74) | CYP2D6KCNH2MAOBGAACYP2C19 | |
| SCHEMBL4875640 | 0.81 | KCNA5 (0.74) | CYP2D6KCNH2MAOBGAACYP2C19 | |
| SCHEMBL15700085 | 0.80 | MC4R (0.65) | CYP2D6KCNH2CHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | HAVCR2, CD44, ENGASE | CYP2D6 4663/4885KCNH2 3229/4885CHRM2 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.