Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901673 | 0.86 | CYP2D6 (0.59) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL11817710 | 0.84 | KCNH2 (0.58) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL18704989 | 0.84 | GRIN2B (0.52) | CYP2D6CYP3A4CYP1A2KCNH2TSHR | |
| SCHEMBL23496077 | 0.83 | CYP2C19 (0.73) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL7089852 | 0.83 | CYP2C19 (0.73) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL4873121 | 0.83 | CYP2C19 (0.73) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL25453185 | 0.81 | CYP2D6 (0.53) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL9366911 | 0.81 | KCNA5 (0.74) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL4875640 | 0.81 | KCNA5 (0.74) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL4874914 | 0.79 | CYP3A4 (0.61) | MAOBCYP2D6CYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | HAVCR2, CD44, ENGASE | MAOB 688/4885CYP2D6 4663/4885CYP3A4 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.