Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26227240 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23902868 | 0.90 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23902874 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL26227168 | 0.87 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23903032 | 0.86 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL26227223 | 0.85 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23256990 | 0.85 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL25500526 | 0.84 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL26227237 | 0.83 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL24513494 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021198213-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | DDT, EPCAM, SLC18A3 | NPC1 1782/4885RAB9A 1937/4885SMN1; SMN2 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.