Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23902918 | 0.91 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23903121 | 0.88 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23902920 | 0.85 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23903240 | 0.82 | NPC1 (0.47) | NPC1RAB9ALMNAALDH1A1CYP1A2 | |
| SCHEMBL23903183 | 0.80 | KDM4E (0.41) | NPC1RAB9AL3MBTL1KDM4EATM | |
| SCHEMBL23903208 | 0.79 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26228146 | 0.78 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23903103 | 0.78 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23903030 | 0.78 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23902917 | 0.76 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021198213-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | DDT, EPCAM, SLC18A3 | NPC1 1782/4885RAB9A 1937/4885SMN1; SMN2 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.