SCHEMBL23903240

SCHEMBL23903240

O=c1c2ccccc2oc2nc3ccc4c(c5ccccc5n4-c4nc(-c5ccc(-c6ccccc6)cc5)nc5ccccc45)c3n12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ACP1 P24666 2/20 0.35
TSHR P16473 3/20 0.34
ABCG2 Q9UNQ0 3/20 0.34
HSD17B10 Q99714 2/20 0.34
MAPK1 P28482 1/20 0.34
GBA1 P04062 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
PDE5A O76074 1/20 0.32
LMNA P02545 3/20 0.31
HTT P42858 1/20 0.31
ACHE P22303 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23903121 0.84 NPC1 (0.45) NPC1RAB9ATSHRHSD17B10ALDH1A1
SCHEMBL23903237 0.82 NPC1 (0.54) NPC1RAB9ATSHRHSD17B10MAPK1
SCHEMBL23902918 0.82 NPC1 (0.47) NPC1RAB9ATSHRHSD17B10ALDH1A1
SCHEMBL25500516 0.79 NPC1 (0.46) NPC1RAB9AACP1TSHRABCG2
SCHEMBL23903159 0.79 ABCG2 (0.39) ACP1ABCG2GBA1ALDH1A1LMNA
SCHEMBL15335181 0.78 ACP1 (0.41) ACP1TSHRABCG2HSD17B10MAPK1
SCHEMBL23903151 0.74 NPC1 (0.48) NPC1RAB9ATSHRHSD17B10MAPK1
SCHEMBL20226345 0.73 ACP1 (0.47) ACP1TSHRABCG2HSD17B10MAPK1
SCHEMBL26227100 0.73 NPC1 (0.57) NPC1RAB9ATSHRABCG2HSD17B10
SCHEMBL19986108 0.73 ACP1 (0.40) NPC1RAB9AACP1TSHRABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151026-A1 MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230151026-A1 MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
WO-2021198213-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151026-A1 MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION DDT, EPCAM, SLC18A3 NPC1 1782/4885RAB9A 1937/4885ACP1 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.