Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.30 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905865 | 0.93 | GABRA5 (0.34) | GABRA5CFTRABCB1ABCC1 | |
| SCHEMBL23905315 | 0.93 | GABRA5 (0.34) | GABRA5CFTRABCB1ABCC1 | |
| SCHEMBL23905286 | 0.93 | GABRA5 (0.33) | GABRA5MAPTCFTRABCB1ABCC1 | |
| SCHEMBL23905269 | 0.93 | CFTR (0.34) | GABRA5CFTRABCB1ABCC1 | |
| SCHEMBL23905318 | 0.92 | GABRA5 (0.32) | GABRA5CFTR | |
| SCHEMBL23904795 | 0.92 | GABRA5 (0.32) | GABRA5CFTR | |
| SCHEMBL23905687 | 0.91 | CFTR (0.33) | GABRA5MAPTCFTR | |
| SCHEMBL23905818 | 0.90 | GABRA5 (0.34) | GABRA5MAPTCFTRABCB1ABCC1 | |
| SCHEMBL23905668 | 0.89 | CFTR (0.34) | GABRA5CFTRADCY8ADCY1 | |
| SCHEMBL23905673 | 0.89 | CFTR (0.32) | GABRA5CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |