Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.59 |
| ▸ | STAT3 | P40763 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | IL1B | P01584 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.50 |
| ▸ | GRAMD1A | Q96CP6 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959687 | 0.91 | CRBN (0.63) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL22959653 | 0.91 | STAT3 (0.62) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL22959805 | 0.90 | STAT3 (0.61) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL22959682 | 0.90 | STAT3 (0.61) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL23884279 | 0.90 | CRBN (0.61) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL29880821 | 0.88 | CRBN (0.71) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL23904588 | 0.87 | CRBN (0.66) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL23884285 | 0.86 | CRBN (0.68) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL21259481 | 0.86 | CRBN (0.67) | CRBNDDB1STAT3CA2DYRK2 | |
| SCHEMBL17536582 | 0.86 | CRBN (0.67) | CRBNDDB1STAT3CA2DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021201577-A1 | HMG-COA REDUCTASE DEGRADATION INDUCING COMPOUND | UPPTHERA (KR) | 2021-10-07 | — | — | WO | disclosed |