Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19119624 | 0.78 | CES1 (0.36) | MEN1KMT2A | |
| SCHEMBL18446031 | 0.75 | — | — | |
| SCHEMBL24001324 | 0.71 | PARP10 (0.34) | PARP10KDM4EPARP1CA1CA2 | |
| SCHEMBL20169824 | 0.70 | CTBP2 (0.34) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL24311856 | 0.69 | SMN1; SMN2 (0.44) | KDM4ECA1CA2MEN1KMT2A | |
| SCHEMBL21156002 | 0.69 | — | — | |
| SCHEMBL23963890 | 0.69 | ALDH1A1 (0.43) | KDM4ENR1H4CA1CA2MEN1 | |
| SCHEMBL28151928 | 0.68 | PLA2G10 (0.53) | PLA2G10PLA2G2APARP10CYP17A1KDM4E | |
| SCHEMBL7149167 | 0.68 | PLA2G10 (0.53) | PLA2G10PLA2G2APARP10CYP17A1KDM4E | |
| SCHEMBL21235456 | 0.68 | GFER (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |