Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251115 | 1.00 | GRM5 (0.36) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL30251077 | 1.00 | GRM5 (0.36) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL30250991 | 1.00 | GRM5 (0.36) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL23882893 | 1.00 | GRM5 (0.36) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL26159468 | 1.00 | GRM5 (0.36) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL30251513 | 0.88 | MAOB (0.32) | — | |
| SCHEMBL23882663 | 0.88 | MAOB (0.32) | — | |
| SCHEMBL23905970 | 0.87 | GRM5 (0.39) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL23882869 | 0.87 | GRM5 (0.39) | GRM5VNN1TNFADRA1DADRA1A | |
| SCHEMBL30251017 | 0.87 | GRM5 (0.39) | GRM5VNN1TNFADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150985-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-18 | — | — | US | disclosed |
| US-20230150985-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150985-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | HLA-DRB1, CD74, HLA-C | GRM5 2303/4885VNN1 2710/4885TNF 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.