Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905595 | 1.00 | CFTR (0.34) | CFTRGABRA5ADORA2AADORA2BADORA1 | |
| SCHEMBL23905687 | 0.93 | CFTR (0.33) | CFTRGABRA5ADORA2AADORA2BADORA1 | |
| SCHEMBL23905299 | 0.92 | CFTR (0.31) | CFTRGABRA5 | |
| SCHEMBL23905830 | 0.92 | CFTR (0.31) | CFTRGABRA5 | |
| SCHEMBL23905825 | 0.92 | CFTR (0.31) | CFTRGABRA5 | |
| SCHEMBL23905728 | 0.92 | GABRA5 (0.34) | CFTRGABRA5 | |
| SCHEMBL23905868 | 0.92 | GABRA5 (0.34) | CFTRGABRA5 | |
| SCHEMBL23905870 | 0.92 | GABRA5 (0.34) | CFTRGABRA5 | |
| SCHEMBL23904877 | 0.91 | CFTR (0.32) | CFTRGABRA5ADORA2AADORA2BADORA1 | |
| SCHEMBL25113797 | 0.90 | CFTR (0.33) | CFTRGABRA5ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |