Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905712 | 1.00 | POLB (0.35) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL24986770 | 0.94 | POLB (0.37) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL24984626 | 0.93 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL24984624 | 0.93 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL24984631 | 0.92 | POLB (0.34) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL24984632 | 0.92 | POLB (0.34) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL23904906 | 0.90 | MAPT (0.33) | POLBMAPTROCK2ROCK1PDE4B | |
| SCHEMBL23905707 | 0.90 | POLB (0.35) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL24986046 | 0.90 | POLB (0.33) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL23905669 | 0.90 | POLB (0.36) | POLBMAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |