Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547368 | 0.88 | CES2 (0.56) | MAPTCES2CES1ALDH1A1HPGD | |
| SCHEMBL13971730 | 0.82 | HDAC1 (0.53) | MAPTCES2CES1ALDH1A1HPGD | |
| SCHEMBL2183846 | 0.78 | CES2 (0.48) | MAPTCES2CES1ALDH1A1HPGD | |
| SCHEMBL3085193 | 0.78 | MAPT (0.47) | MAPTCES2CES1ALDH1A1HPGD | |
| SCHEMBL13293382 | 0.78 | CES2 (0.48) | CES2CES1ALDH1A1TSHRHDAC1 | |
| SCHEMBL9720573 | 0.77 | PPARA (0.46) | MAPTALDH1A1HPGDTSHRPPARA | |
| SCHEMBL8256684 | 0.77 | PIM1 (0.55) | MAPTALDH1A1HPGDTSHRPPARA | |
| SCHEMBL9720643 | 0.77 | HDAC1 (0.58) | MAPTALDH1A1HPGDTSHRGAA | |
| SCHEMBL8159099 | 0.76 | MAPT (0.46) | MAPTCES2CES1ALDH1A1HPGD | |
| SCHEMBL3549232 | 0.76 | MAPT (0.50) | MAPTCES2CES1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |