Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25114393 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL23905738 | 0.87 | HSD17B2 (0.46) | ALDH1A1PTPN11MAPTPOLBGAA | |
| SCHEMBL30596879 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL23930154 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL26110237 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL30596874 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL23904780 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL23905296 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL23905306 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1PTPN11CYP3A4MAPT | |
| SCHEMBL23905313 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1PTPN11CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |