Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905707 | 0.94 | POLB (0.35) | POLBTRPV1KMT2AMEN1HPGD | |
| SCHEMBL23905704 | 0.91 | POLB (0.34) | POLBTRPV1KMT2AMEN1HPGD | |
| SCHEMBL23905267 | 0.89 | POLB (0.35) | POLBTRPV1KMT2AMEN1HPGD | |
| SCHEMBL23905712 | 0.89 | POLB (0.35) | POLBTRPV1KMT2AMEN1HPGD | |
| SCHEMBL23905710 | 0.89 | POLB (0.34) | POLBTRPV1KMT2AMEN1HPGD | |
| SCHEMBL24345458 | 0.88 | POLB (0.37) | POLBKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL24345299 | 0.87 | POLB (0.36) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL24345459 | 0.86 | POLB (0.39) | POLBKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL24985387 | 0.86 | POLB (0.36) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL24985386 | 0.86 | POLB (0.36) | POLBKMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |