SCHEMBL23905489

SCHEMBL23905489

Cc1cnc2c(OC3CC3)cc(C(=O)NC[C@](O)(c3cc4c(c(-c5ccc(F)cc5)n3)OCC4(CF)CF)C(F)(F)F)cc2c1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GABRA5 P31644 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24987243 0.93 GABRA5 (0.34) GABRA5
SCHEMBL23905865 0.92 GABRA5 (0.34) GABRA5
SCHEMBL23905315 0.92 GABRA5 (0.34) GABRA5
SCHEMBL25117147 0.92 GABRA5 (0.32) GABRA5
SCHEMBL25115971 0.92 GABRA5 (0.32) GABRA5
SCHEMBL23905266 0.92 GABRA5 (0.31) GABRA5
SCHEMBL23905251 0.90 GABRA5 (0.32) GABRA5
SCHEMBL24987242 0.90 GABRA5 (0.32) GABRA5
SCHEMBL24988224 0.90 GABRA5 (0.32) GABRA5
SCHEMBL26527274 0.90 GABRA5 (0.32) GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021198981-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF Janssen Biopharma, Inc. (US) 2021-10-07 WO disclosed