Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 3/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345317 | 0.92 | POLB (0.34) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL23195916 | 0.91 | POLB (0.38) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL23196057 | 0.89 | POLB (0.30) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL24345844 | 0.89 | POLB (0.36) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL24345474 | 0.88 | POLB (0.35) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL23195679 | 0.88 | MAPK13 (0.32) | — | |
| SCHEMBL23195701 | 0.86 | BTK (0.31) | POLBLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL24987082 | 0.85 | ALDH1A1 (0.36) | POLBALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL24984617 | 0.85 | ALDH1A1 (0.36) | POLBALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL23195908 | 0.85 | MAPK14 (0.36) | LMNAALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |