Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905374 | 1.00 | CFTR (0.33) | CFTRCYP2C9IDO1GRM2KCNH2 | |
| SCHEMBL23905375 | 0.90 | CFTR (0.33) | CFTRCYP2C9IDO1GRM2 | |
| SCHEMBL23905407 | 0.90 | CFTR (0.33) | CFTRGRM2KCNH2CYP3A4ALOX5 | |
| SCHEMBL31412435 | 0.90 | CFTR (0.33) | CFTRGRM2KCNH2CYP3A4ALOX5 | |
| SCHEMBL23905581 | 0.90 | CFTR (0.33) | CFTRGRM2KCNH2CYP3A4ALOX5 | |
| SCHEMBL23904871 | 0.90 | CFTR (0.33) | CFTRKCNH2CYP3A4TRPV1CSNK1D | |
| SCHEMBL23905616 | 0.90 | DPP4 (0.36) | CFTRCYP2C9CYP3A4GABRA5 | |
| SCHEMBL24986093 | 0.90 | CFTR (0.41) | CFTRCYP2C9IDO1GRM2KCNH2 | |
| SCHEMBL23904764 | 0.89 | CFTR (0.33) | CFTRCYP2C9IDO1TRPV1 | |
| SCHEMBL23904755 | 0.89 | CFTR (0.33) | CFTRCYP2C9IDO1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |