Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905374 | 0.90 | CFTR (0.33) | GABRA5CYP2C9CFTRCYP3A4 | |
| SCHEMBL23905533 | 0.90 | CFTR (0.33) | GABRA5CYP2C9CFTRCYP3A4 | |
| SCHEMBL23905693 | 0.88 | GABRA5 (0.33) | DPP4GABRA5RORCCYP2C8CYP2C9 | |
| SCHEMBL23904871 | 0.87 | CFTR (0.33) | CFTRPTGS2CYP3A4 | |
| SCHEMBL31412435 | 0.87 | CFTR (0.33) | CFTRPTGS2CYP3A4 | |
| SCHEMBL23905407 | 0.87 | CFTR (0.33) | CFTRPTGS2CYP3A4 | |
| SCHEMBL23905581 | 0.87 | CFTR (0.33) | CFTRPTGS2CYP3A4 | |
| SCHEMBL24986093 | 0.87 | CFTR (0.41) | RORCCYP2C9CFTRCYP3A4 | |
| SCHEMBL23904755 | 0.86 | CFTR (0.33) | CYP2C9CFTR | |
| SCHEMBL23904764 | 0.86 | CFTR (0.33) | CYP2C9CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |