Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905544 | 0.87 | HCAR2 (0.37) | PSMD14KDM4EGAACNR2CCR1 | |
| SCHEMBL23905404 | 0.85 | ATM (0.47) | ATMPSMD14KDM4EALDH1A1GAA | |
| SCHEMBL30007783 | 0.83 | KDM4E (0.39) | ATMPSMD14KDM4EALDH1A1GAA | |
| SCHEMBL23930065 | 0.83 | KDM4E (0.39) | ATMPSMD14KDM4EALDH1A1GAA | |
| SCHEMBL23196217 | 0.82 | ATM (0.44) | ATMPSMD14KDM4EALDH1A1HPGDS | |
| SCHEMBL25687961 | 0.81 | ATM (0.41) | ATMPSMD14KDM4EALDH1A1HPGDS | |
| SCHEMBL18458757 | 0.79 | ATM (0.50) | ATMPSMD14KDM4EALDH1A1GAA | |
| SCHEMBL25114201 | 0.78 | KDM4E (0.50) | ATMPSMD14KDM4EALDH1A1GAA | |
| SCHEMBL17442622 | 0.77 | ATM (0.51) | ATMPSMD14KDM4EALDH1A1GAA | |
| SCHEMBL26577806 | 0.76 | CCR1 (0.39) | PSMD14KDM4ECCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |