Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930065 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1POLBNR1I2MEN1 | |
| SCHEMBL23930195 | 0.86 | CA12 (0.35) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL30007888 | 0.86 | CA12 (0.35) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL30211269 | 0.85 | TSHR (0.34) | KDM4EPOLBTDP1NPC1RAB9A | |
| SCHEMBL23905572 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1POLBMEN1HPGD | |
| SCHEMBL23905543 | 0.83 | ATM (0.42) | KDM4EALDH1A1POLBNR1I2PSMD14 | |
| SCHEMBL30007681 | 0.82 | NOTUM (0.41) | KDM4EALDH1A1POLBMEN1HPGD | |
| SCHEMBL23930098 | 0.82 | NOTUM (0.41) | KDM4EALDH1A1POLBMEN1HPGD | |
| SCHEMBL23905354 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL23905582 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1POLBMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |