Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 3/20 | 0.31 |
| ▸ | MAX | P61244 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25115578 | 0.85 | HCAR2 (0.36) | HCRTR1HCRTR2MKNK2CA12CA1 | |
| SCHEMBL23930195 | 0.83 | CA12 (0.35) | CA12CA1CA2CA3PKM | |
| SCHEMBL30007888 | 0.83 | CA12 (0.35) | CA12CA1CA2CA3PKM | |
| SCHEMBL23904745 | 0.79 | CA12 (0.50) | CA12CA1CA2CA3PKM | |
| SCHEMBL30006713 | 0.77 | EGLN1 (0.35) | HCRTR1HCRTR2CA12CA1CA2 | |
| SCHEMBL23958617 | 0.77 | EGLN1 (0.35) | HCRTR1HCRTR2CA12CA1CA2 | |
| SCHEMBL23904799 | 0.76 | KMT2A (0.41) | CA12CA1CA2CA3PKM | |
| SCHEMBL23930093 | 0.76 | CA12 (0.39) | CA12CA1CA2CA3PKM | |
| SCHEMBL30007379 | 0.76 | CA12 (0.39) | CA12CA1CA2CA3PKM | |
| SCHEMBL23905562 | 0.71 | CA12 (0.44) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |