Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905481 | 0.94 | AR (0.34) | HRH1KCNH2 | |
| SCHEMBL23905243 | 0.94 | AR (0.34) | HRH1KCNH2 | |
| SCHEMBL23905482 | 0.94 | AR (0.34) | HRH1KCNH2 | |
| SCHEMBL23905449 | 0.87 | GABRA5 (0.33) | HRH1KCNH2 | |
| SCHEMBL23905268 | 0.87 | AR (0.34) | — | |
| SCHEMBL24985122 | 0.86 | AR (0.34) | — | |
| SCHEMBL24985121 | 0.86 | AR (0.34) | — | |
| SCHEMBL23905260 | 0.85 | AR (0.33) | — | |
| SCHEMBL24984629 | 0.85 | AR (0.33) | — | |
| SCHEMBL24986142 | 0.85 | GABRA5 (0.32) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |