SCHEMBL23905799

SCHEMBL23905799

OCC(O)(c1cc2c(c(-c3ccc(F)cc3)n1)OCC21COC1)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.32
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23904885 1.00 CYP2C9 (0.32) CYP2C9IDO1
SCHEMBL23904887 0.91
SCHEMBL23905455 0.85
SCHEMBL23905493 0.84 CYP2C9 (0.33) CYP2C9IDO1
SCHEMBL23904749 0.82 GRM2 (0.32)
SCHEMBL23905725 0.81
SCHEMBL23905784 0.78
SCHEMBL23904890 0.78 PTGS2 (0.33)
SCHEMBL23905801 0.77
SCHEMBL23905618 0.75 ADORA2A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021198981-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF Janssen Biopharma, Inc. (US) 2021-10-07 WO disclosed