SCHEMBL23906014

SCHEMBL23906014

CSc1ccc(C(Oc2c(F)cc3c(c2C)OCCC3=O)c2ccc(C#N)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.35
ALOX5 P09917 1/20 0.32
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23882653 0.89 MAOB (0.36) MAOBGRM5
SCHEMBL30251566 0.89 MAOB (0.36) MAOBGRM5
SCHEMBL30251186 0.89 MAOB (0.36) MAOBGRM5
SCHEMBL30251592 0.88 MAOB (0.36) MAOBGRM5
SCHEMBL23882710 0.88 MAOB (0.36) MAOBGRM5
SCHEMBL23882949 0.87 MAOB (0.35) MAOBGRM5
SCHEMBL30250946 0.87 MAOB (0.35) MAOBGRM5
SCHEMBL30251071 0.87 MAOB (0.35) MAOBGRM5
SCHEMBL23882732 0.86 PTGS2 (0.36) MAOB
SCHEMBL30251480 0.86 PTGS2 (0.36) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021198283-A1 INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR JANSSEN PHARMACEUTICA NV (BE) 2021-10-07 WO disclosed