⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451689 | 0.80 | TRPA1 (0.32) | — | |
| SCHEMBL22640662 | 0.71 | — | — | |
| SCHEMBL24520695 | 0.69 | — | — | |
| SCHEMBL14767897 | 0.69 | — | — | |
| SCHEMBL14145715 | 0.69 | — | — | |
| SCHEMBL23892235 | 0.67 | TRPA1 (0.35) | — | |
| SCHEMBL18597155 | 0.66 | — | — | |
| SCHEMBL21207683 | 0.66 | TRPA1 (0.31) | — | |
| SCHEMBL20061654 | 0.64 | TRPA1 (0.32) | — | |
| SCHEMBL7294109 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202480-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |