Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 18/20 | 0.79 |
| ▸ | GAA | P10253 | 16/20 | 0.79 |
| ▸ | NPC1 | O15118 | 14/20 | 0.79 |
| ▸ | RAB9A | P51151 | 14/20 | 0.79 |
| ▸ | MEN1 | O00255 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.79 |
| ▸ | HTT | P42858 | 6/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280286 | 0.88 | MAPT (1.00) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL23657817 | 0.86 | MAPT (0.58) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL880223 | 0.84 | GAA (1.00) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL880461 | 0.83 | MAPT (0.76) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL10280285 | 0.83 | MAPT (0.73) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL15359675 | 0.82 | MAPT (0.76) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL10280287 | 0.82 | MAPT (0.76) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL14942678 | 0.80 | MAPT (0.68) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL880195 | 0.78 | GAA (0.75) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL880217 | 0.78 | FAAH (0.66) | MAPTGAANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021200934-A1 | ANTIMALARIAL DRUG | 国立大学法人 長崎大学 | 2021-10-07 | — | — | WO | disclosed |