Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15313304 | 0.89 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL28840060 | 0.84 | NR1H2 (0.49) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL21913758 | 0.84 | NR1H2 (0.49) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| Hydrochloric Acid SCHEMBL29596834 | 0.83 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL29344011 | 0.82 | NR1H2 (0.48) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL23231374 | 0.82 | NR1H2 (0.48) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL25409415 | 0.80 | NR1H2 (0.56) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL1979623 | 0.80 | NR1H2 (0.56) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL994561 | 0.80 | NR1H2 (0.56) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 | |
| SCHEMBL16759817 | 0.79 | NR1H2 (0.58) | NR1H2USP2SMN1; SMN2KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203131-A1 | SUBSTITUTED PYRIMIDINES AND METHODS OF USE | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2021-10-07 | — | — | WO | disclosed |