Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773503 | 0.94 | KMT2A (0.57) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL5990029 | 0.94 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL6181838 | 0.88 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| Methoxymethane SCHEMBL27278268 | 0.84 | MAPT (0.73) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL29207027 | 0.83 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL7168347 | 0.83 | MAPT (0.71) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL3599787 | 0.83 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL1068092 | 0.81 | MAPT (0.69) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL9786970 | 0.81 | MAPT (0.74) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL6751643 | 0.81 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892602-A1 | METHOD FOR THE PREPARATION OF DEUTERATED OR TRITIATED COMPOUNDS | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2021-10-13 | — | — | EP | disclosed |