Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601201 | 0.90 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL30832832 | 0.90 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29192895 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL15568228 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11622125 | 0.84 | HRH3 (0.48) | KDM4EALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL28180523 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL23907027 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9062685 | 0.83 | NPC1 (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL28881046 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9079991 | 0.83 | PDGFRB (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383079-B | Metal organic framework material based on alkyl mercaptan modification and synthetic method thereof | 广东工业大学 | 2020-06-09 | — | — | CN | claimed |
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2021198883-A1 | SYNTHESIS OF OLIGONUCLEOTIDES AND RELATED COMPOUNDS | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |
| CN-111315735-A | Dihydrobenzimidazolones | C4医药公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-107383079-B | Metal organic framework material based on alkyl mercaptan modification and synthetic method thereof | 广东工业大学 | 2020-06-09 | — | — | CN | disclosed |