Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 5/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903327 | 0.83 | BAZ2B (0.56) | RAB9AALDH1A1MAPTMKNK1EIF4E | |
| SCHEMBL11898576 | 0.79 | TP53 (0.58) | RAB9AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL29606569 | 0.77 | MKNK1 (0.52) | MKNK1EIF4EMKNK2LRRK2PIK3CD | |
| SCHEMBL12545542 | 0.77 | KMT2A (0.64) | KDM4EALDH1A1HPGDMAPTMKNK1 | |
| SCHEMBL25601967 | 0.75 | POLB (0.63) | POLBRAB9AKDM4EHPGDMAPT | |
| SCHEMBL17423636 | 0.75 | MKNK1 (0.47) | KDM4EMAPTMKNK1EIF4EMKNK2 | |
| SCHEMBL20418723 | 0.74 | MKNK1 (0.49) | KDM4EMKNK1EIF4EMKNK2LRRK2 | |
| SCHEMBL20086323 | 0.74 | MKNK1 (0.55) | MKNK1EIF4EMKNK2LRRK2 | |
| SCHEMBL19674259 | 0.74 | MKNK1 (0.55) | MKNK1EIF4EMKNK2LRRK2PIK3CD | |
| SCHEMBL5947048 | 0.73 | MAPT (0.48) | KDM4EALDH1A1MAPTMKNK1EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198883-A1 | SYNTHESIS OF OLIGONUCLEOTIDES AND RELATED COMPOUNDS | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |